| Clinical Results of Endovascular Mechanical Thrombectomy for Acute Ischemic Stroke in Octogenarian Patients
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Yong Hag Cho , Hee Sup Shin , Seung Hwan Lee , Jun Seok Koh , Hak Cheol Ko |
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Department of Neurosurgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea |
| 80세 이상의 초고령 환자에서 발생한 급성 뇌경색에서 뇌혈관내 기계적 혈전제거술의 임상 결과
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조용학·신희섭·이승환·고준석·고학철 |
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경희대학교 의과대학 강동경희대학교병원 신경외과학교실
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| Abstract |
Objective
There are limited data about the outcomes after mechanical thrombectomy(MT) for patients aged over 80. We evaluated the outcomes and characteristics of very elderly patients who were treated with MT for acute ischemic stroke.
Methods
Between January 2014 and December 2017, 128 patients with acute intracranial large vessel occlusion were treated with MT at our institute, and 41 patients were age of ≥70 years. We compared outcomes between elderly patients (≥70 and <80 years, n=25) and very elderly patients(≥80 years, n=16), and assessed prognostic factors for favorable outcomes(modified Rankin Scale score[mRS] 0-2) at 90 days in all patients.
Results
There was no significant difference in initial National Institutes of Health Stroke Scale(iNIHSS) score and underlying disease between the 2 groups(p=0.594). The internal carotid artery occlusion was observed more frequently in very elderly patients(43.8% versus 12.0%, p=0.147). Successful revascularization(modified Thrombolysis in Cerebral Infarction[mTICI] scores 2b/3)(37.5% versus 68.8%, p=0.055) and complete recanalization(mTICI 3)(25.0% versus 40.0%, p=0.323) were achieved more frequently in elderly patients, but the differences did not reach statistical signifi- cance. The favorable outcome of mRS 0-2 was observed in 13(31.7%), and death at 90 days was 8(19.5%) in very elderly patients, but it did not show significant differences between two groups.
Conclusion
Octogenarian patients with MT treatment for acute ischemic stroke showed comparable treatment results of successful recanalization and favorable clinical outcome with those who were younger than 80. |
| Key Words:
Acute stroke, Mechanical thrombectomy, Octogenarian, Elderly
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