Gamma Knife Surgery for Metastatic Brain Tumors Above 75 Years |
Min-Choel Park1 , Hyok-Rae Cho1 , Yong-Soek Park1 , Moo-seong Kim2 |
1Department of Neurosurgery, Kosin University Gospel Hospital, Busan,
2Department of Neurosurgery, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea |
75세 이상의 전이성 뇌종양의 감마나이프 방사선수술 |
박민철1·조혁래1·박용석1·김무성2 |
고신대학교 복음병원 신경외과학교실1, 인제대학교 의과대학 부산백병원 신경외과학교실2 |
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Abstract |
Objective GK Radiosurgery is minimally invasive, safe, and effective way to control local tumor progression and prolong survival.
Methods We treated 40 metastatic brain tumor patients with Gamma-Knife radiosurgery from January 2011 to December 2015. 12 patients were enable to follow-up. Male to female ratio was 2:1, mean age was 79.4 years (75-90 years). Mean Karnofsky performance scale was 84.7 (70-90). Mean tumor volume was 11.6 cc (0.1-35.85 cc). Maximal dose range from 20-40 Gy (mean 26.5 Gy), marginal dose range from 10-18 Gy (mean 13.6 Gy).
Results Primary tumors sites were all lung cancers. lesion site was 2 single lesions and 9 multiple lesions. Survival time was mean 9.3 months (2-29 months) Single metastatic brain tumor was much longer survival than multiple tumor. Most of them died of other problem than nervous system problem.
Conclusion The local control of brain metastases has been shown to improve the quality and length of survival in elderly patients with systemic malignancies. |
Key Words:
Gamma Knife radiosurgery, Metastatic brain tumors |
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