| The Influence of Antiplatelet and/or Anticoagulant Agents on Recurrence of Chronic Subdural Hematoma |
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Hyun Gon Kim , Han San Oh , Tae Wan Kim , Kwan Ho Park |
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Department of Neurosurgery, VHS Medical Center, Seoul, Korea |
| 항혈소판제, 항응고제 복용이 만성 경막하 출혈의 재발에 미치는 영향 |
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김현곤·오한산·김태완·박관호 |
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중앙보훈병원 신경외과 |
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| Abstract |
Objective
The use of antiplatelet agents and anticoagulants has increased in the elderly. The effects of these agents on the development and growth of chronic subdural hematoma (CSDH) are not clear. The purpose of this study was to analyze the clinical features of patients treated with antiplatelet agents and anticoagulants for the treatment of CSDH.
Methods
A retrospective study was performed on 92 patients with CSDH from January 2010 to December 2012. All patients were underwent surgery with burr hole trephination and hematoma drainage. We divided the patients into three groups according to medication history (A: no medication, B: antiplatelet agents, and C: anticoagulants with/without antiplatelet agents). Trauma history, chief complaint on admission, bilaterality of hematoma, international normalized ratio (INR) prolongation, and recurrence rate were reviewed.
Results
There were no statistically significant differences in trauma history, chief complaint on admission, and bilaterality of hematoma between the three groups. INR prolongation and recurrence more commonly occurred in the anticoagulant group compared with the no-medication group (p=0.003, 0.003).
Conclusion
Use of anticoagulants is statistically associated with INR prolongation and increased recurrence. Also, the recurrence rate of CSDH was higher in the antiplatelet agent using group than in the no-medication group. Therefore, more caution and follow-up will be needed after surgery in patients given medication. |
| Key Words:
AntiplateletㆍAnticoagulantㆍSubdural hematomaㆍRecurrence |
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