Journal of Korean Society of Geriatric Neurosurgery 2011;7(1):49-52.
Published online June 30, 2011.
Unusual Radiologic Findings of Chronic Cerebral Paragonimiasis
Hwan-Joo Lee , Dong-Hyuk Park , Shin-Hyuk Kang , Yong-Gu Chung
Department of Neurosurgery, Korea University College of Medicine, Seoul, Korea
Abstract
The authors report a fatal case of chronic cerebral paragonimiasis with unusual clinical course and imaging findings. A 70-yr-old woman presented with complex partial status epilepticus. Her medical history was unknown, but serologic results and sonogram revealed liver cirrhosis. Computed tomography scans of the brain revealed mixed density calcified masses surrounded by porencephaly in the right temporal lobe. Parasite specific antibody test in serum and cerebrospinal fluid by Enzyme-linked immunosorbent assay (ELISA) supported the diagnosis of cerebral paragonimiasis despite atypical radiologic findings. Vigorous managements failed to improve her condition and mentation. The patient died on the fifth day of admission. When unusual calcified intracranial mass exist, parasitic infection should be considered even though it is not often these days. Moreover, early diagnosis with ELISA and aggressive treatments including surgical options should be con sidered even in stable chronic cerebral paragonimiasis, because of the possibility of sudden deterioration.
Key Words: Central Nervous System Parasitic InfectionㆍEnzyme-linked Immunosorbent assayㆍParagonimiasisㆍStatus Epilepticusㆍ Computed Tomography


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