| Surgical Treatment and Outcomes of Pituitary Macroadenomas in the Elderly |
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Jae-Yoel Kwon1 , Chan-Soon Park2 , Jae-Taek Hong1 , Jae-Hoon Sung1 , Byung-Chul Son1 , Sang-Won Lee1 , Seung-Ho Yang1 |
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Departments of Neurosurgery1 and Otorhinolaryngology-HNS2, St. Vincent’s Hospital,
The Catholic University of Korea, Suwon, Korea |
| 뇌하수체 샘종을 가진 노인 환자의 수술적 치료와 임상 결과 |
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권재열1ㆍ박찬순2ㆍ홍재택1ㆍ성재훈1ㆍ손병철1ㆍ이상원1ㆍ양승호1 |
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가톨릭대학교 의과대학 성빈센트병원 신경외과학교실1, 이비인후과학교실2 |
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| Abstract |
Objective
Pituitary adenomas (PA) in the elderly represent an increasing proportion of pituitary tumors, making the surgical management of these patients of special importance. We reviewed our experiences of PA surgery in this age group.
Methods
A retrospective study was performed on 17 patients, aged more than 65 years at the time of surgery.
Results
A total of 17 patients were enrolled for the study. The most common symptoms were visual field defect and blurred vision. The median duration of the symptom was 6 months. Three patients presented with pituitary apoplexy. All patients had pituitary macroadenomas. Hypopituitarism, low serum level of thyroid-stimulating hormone, acromegaly and prolactinoma were diagnosed in 4, 2, 1 and 1 patients, respectively. Tumor removal was performed with transsphenoidal approach in 16 patients and craniotomy in 1. Total resection was achieved in 10 patients. The vision was improved in 5 out of 10 patients with visual disturbances. There was no surgery-related complication except for diabetes insipidus in 1 patient.
Conclusion
Transsphenoidal approach is well tolerated even in elderly patients. Visual deterioration and hypopituitarism in the elderly should not be missed as common age-related diseases. |
| Key Words:
Pituitary tumorsㆍElderlyㆍTranssphenoidal surgeryㆍVisionㆍHypopituitarism |
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